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OCR: en Vitiligo, in which there is patchy and of symmetrical depigmentation of the skir tation (Fig. surrounded by areas of increased pigmer ses of 9.5), occurs in ten to twenty per cent of c invariably Addison's disease. Its presence is almost il failure is an indication that the cause of the adrer tients auto- immune adrenalitis. One of the p aph had described by Addison in his 1855 monog only case extensive vitiligo; however, this was th amination in which permission for post-mortem e was refuser